Objectives:

• Revise the motivations for molecular nanotechnology, redirect R&D resources away from alternative pathways to continuation of Moore’s Law.
• Outline the long, multi-phase development path on the experimental side.
  • Prove physical plausibility by shrinking the uncertainty in required parallelism and attainable reaction frequencies.
  • Highlight new technologies (organotin tripods) that must be developed proactively, to arrive just on schedule for the later development phases.
  • Take action to break the barrier to entry for Phase I.
• Outline the ambitions for a CAD software suite, which will lead to improved clarity on the more far-term development phases.
  • PyTorch for nanomachines. Importance of ergonomic API design and greater programmability, unlocking more control for the user. This often comes with negative effects on backend performance (CPU–GPU communication gap) and a higher barrier to entry (more extensive tutorial suite).
  • The need to restrict the software stack to Apple silicon and high-end Windows PCs (AVX2, discrete GPUs).
  • The strange realization that simulators are out of scope for the CAD foundation.

Table of Contents:

• Experimental Development Pathway
• Principal Issue
• Near-Term
  • Experiments (Phase I–II)
  • Commercialization (Phase III)
• CAD Software
  • Motivation (Phase IV)
  • Influencing Documents (Phase IV)
  • Implementation Plan (Phase V–VI)

© 2025. Philip A. Turner. Permissively licensed.
Drafted in collaboration with the open source community.